Experimental pharmacology practicals are designed to teach concepts and techniques through demonstrations and experiential learning by the students who have never performed experiments. The main goal of the study is to evaluate the preference and acceptance about the demonstrations of the various animal experiments and to assess impact of experiential learning. Demonstrations of animal experiment were done by teachers and then same experimental exercise done by students in group. A total 120 students attended the exercise and performed the experiment. Statistical analysis was performed to evaluate acceptance, preference and impact of both teaching and learning tool. The study result revealed that students accept the demonstration as teaching tool but prefer and have good impact of experiential learning to improve skill, knowledge and experience about experimental techniques.