Variations of coronary orifices may change in advanced age because aortic root pathologies and especially systemic hypertension are much more common in later decades of life. These morbidities may affect the presentation of abnormalities of the coronary anatomy. In our study out of 80 heart specimens we observed 4 specimens with two coronary Ostia emerging from the anterior aortic sinus of the right coronary sinus related to the right coronary artery, which intend gives third coronary artery an anomalous opening from the right coronary artery was photographed and the incidence of 5% was recorded. The awareness of anatomical relation of the coronary orifices may decrease the morbidity and mortality of such invasive procedures. An accessory origin of the coronary orifices may disturb performing an aortotomy incision for aortic valve exposure, preparing a coronary button in root replacement, direct delivery of cardioplegia through the coronary orifices, and approaches for aortic root enlargement.