Haematological parameters show substantial variability in different ethnic populations, in which predisposition to anemia is a major factor. Findings in patients with subclinical hypothyroidism and primary hypothyroidism illustrates that even minor alterations in serum thyroid function tests can have important consequences for a variety of thyroid hormone-related clinical endpoints. In the last few years, several studies described variations in hematological parameters in hypothyroidism-a type of thyroid dysfunction, where Hb, MCV, RDW, HCT and RBC: a several hematological indices have shown substantial increases than normal reference range in this disorder and have correlation with minor alteration of serum thyroid hormones. In this review, we discuss the variations in hematological parameters in hypothyroidism and its management. We discuss the possible consequences of these studies for the patients and also new insight in thyroid hormone action and haematology from these data. We have also touched about the screening of thyroid profile and haematological parameters,an important information to general public for clinical and diagnostic use.