Oral medication delivery system research has resulted in the development of new formulations and technology. Such studies demonstrate the importance of the oral route among patients. We__ampersandsignrsquo;ve gone through all of the benefits and drawbacks of medicated chewing gum as a contemporary medication delivery system, including the history, benefits and drawbacks, production processes, composition variations, assessment tests, and samples of different medicated chewing gum kinds. The acceptance of medicated chewing gum has grown over time. Chewing gum__ampersandsignrsquo;s advantages and therapeutic benefits encourage its development, as shown by the fact that new formulations including new pharmaceuticals have been generated in the past and will be found in the market by the formation of new medicated chewing gums. Medicated chewing gums have a broad range of potential uses that will be identified in the future. Chewing gums now have the same qualification criteria as pills. Patients__ampersandsignrsquo; compliance is improved by using medicated chewing gums as a delivery strategy in patient-centered research.