Musa acuminata (Musaceae) is a tropical and subtropical perennial tree-like plant that grows in various tropical and subtropical locations throughout the world. Because of its nutrient-dense diet and varied medicinal qualities, bananas, which may be eaten as a fruit or a vegetable, are one of the most important crops in many countries. Bananas include apigenin glycosides, myricetin glycoside, myricetin-3-O-rutinoside, delphinidin, pelargonidin, peonidin, malvidin, naringenin glycosides, kaempferol-3-O-rutinoside, dopamine, N-acetyl serotonin, rutin, polyphenols, flavonoids, total dietary fibre, The main aim of this study is to validate and highlight M. acuminata__ampersandsignrsquo;s medicinal and nutritional benefits. According to a literature study, fever, cough, bronchitis, dysentery, allergy diseases, sexually transmitted infections, and some non-communicable disorders have all been related to M. acuminata. Antioxidant, anti-diabetic, immunomodulatory, hypolipidemic, anti-cancer, and anti-microbial activities have been found for M. acuminata. Pharmacological investigations support the medicinal plant__ampersandsignrsquo;s traditional importance, indicating that indigenous peoples utilised M. acuminata to treat and cure a wide range of diseases and disorders. Individual bioactive constituent(s) from distinct parts of this plant, on the other hand, need to be investigated further in order to verify various pharmacological claims and to explore the potential of M. acuminata in drug development and use in functional foods. In order to create efficient disease prevention and management strategies, a comprehensive study of M. acuminata__ampersandsignrsquo;s biological activity is given, as well as possible mechanisms and phytochemicals involved.