Capparidaceae family includes the evergreen shrub Buchholzia coriacea (Wonderful cola), which may be found in Cameroon, Central African Republic, Gabon, Congo, Angola, Nigeria, and Ghana, among other locations. Diarrhea, malaria, rheumatism, ulcers, worm infestation, asthma and cough, diabetes, hypertension, mental disorders, and impotence were among the diseases for which conventional medicine saw it as a viable alternative therapy. Some of its ethnomedicinal knowledge have been ethnic pharmacologically validated and published in peer-reviewed journals. As a consequence, the focus of this research is on a current assessment of its confirmed ethnomedicinal activities, which will serve as a research horizon for present and future researchers.