Drug delivery systems are formulations that convey medicine to the target site of action inside the body. A good carrier protects the medicine from being broken down or removed quickly, resulting in higher drug concentration in the target tissues. Because of their biodegradability, biocompatibility, and non-immunogenic character, niosomes, which are formed by the self-association of non-ionic surfactants and cholesterol in an aqueous phase, are prospective drug carriers. In recent years, several study articles have been published in scientific publications describing the capacity of niosomes to function as a carrier for the delivery of different types of drugs. The present study examines niosomal drug delivery systems__ampersandsignrsquo; manufacturing processes, characterization methodologies, and latest research, as well as offering up-to-date information on novel niosomal drug delivery applications.