In a vesicular drug delivery system, one or more concentric bilayers of amphiphilic molecules cover an aqueous compartment. They are an excellent distribution method for targeted medication administration because of their ability to localise drug activity to the area or organ of function. The vesicular drug delivery system maintains the drug activity at a constant rate. As a consequence, the body__ampersandsignrsquo;s opioid frequency is maintained while unfavourable side effects are reduced. Unsaturated fatty acid vesicles are known as ufasomes. With a pH range of 7 to 9, they__ampersandsignrsquo;re pH-controlled suspensions of closed lipid bilayers made up of fatty acids and their ionised species (soap). Fatty acid vesicles are often made using the lipid film hydration technique. Oleic acid is the most significant fatty acid utilised as a primary component in the production of ufasomes. This study discusses the advantages, disadvantages, possible development, and categorization of ufasomes.