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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Open Science Publishers LLP</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">163</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url"/><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>EVALUATION OF EFFICACY AND SAFETY OF NUTRICHARGE__ampersandsignreg;S__ampersandsignamp;F (AN NATURAL SUPPLEMENT) ON WEIGHT MAINTENANCE:__ampersandsignnbsp;A RANDOMIZED, PROSPECTIVE, DOUBLE BLIND, PLACEBO CONTROLLED STUDY&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ravichand</surname><given-names>D.M.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Vukkala</surname><given-names>Rajesh</given-names></name></contrib><contrib contrib-type="author"><name><surname>Reddy</surname><given-names>D. Ravishekar</given-names></name></contrib><contrib contrib-type="author"><name><surname>Kapoor</surname><given-names>Kapeel</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>30</day><month>09</month><year>2015</year></pub-date><volume/><issue/><fpage>11</fpage><lpage>18</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Aim: The aim of the present investigation is to evaluate the efficacy of Nutricharge__ampersandsignreg; S__ampersandsignamp;F on weight maintenance in obese subjects by monitoring the changes in Body Weight, Body Mass Index (BMI), Body fat analysis and Waist circumference. The study was conducted for assessing the safety and tolerability of Nutricharge__ampersandsignreg; S__ampersandsignamp;F. As a secondary objective the quality of life was assessed by using the Moorehead Ardelt questionare. Methodology: The study was designed in 6 phases comprising of screening, treatment period, telephonic survey and end of the visit. A total of 117 subjects were enrolled based on the inclusion and exclusion criteria. Eligible subjects were randomly assigned either to Nutricharge__ampersandsignreg; S__ampersandsignamp;F (investigational arm) or to matching placebo (placebo arm) in the ratio of 4:1. The general physical examination including measurement of pulse, respiratory rate, temperature, blood pressure, and systemic examination of major systems namely cardiovascular system (CVS), central nervous system (CNS), gastrointestinal (GI) and respiratory system were measured and monitored during the study. The anthropometric measurements such as Height, weight, BMI, Body fat analysis and waist circumference were also assessed. The change in the anthropometric measurements (Body Mass Index (BMI), body fat analysis and waist circumference) from baseline visit (Phase 2) to after Day 90 __ampersandsignplusmn; 3 (Phase 5) of treatment were determined. Safety of the investigational product was assessed from the number of adverse events occurred and judging their causal relationship to the study drug. Results and Conclusion: It was found that by using the Nutricharge the weight and BMI in the treatment groups were significantly decreased showing the potentiality of the Nutricharge S __ampersandsignamp; F towards the obesity disorders. It can be concluded that the Nutricharge S __ampersandsignamp; F is an excellent product for reducing obesity and is safe for use.&#13;
</p></abstract><kwd-group><kwd>Obesity</kwd><kwd> Metabolic disorder</kwd><kwd> Nutritional supplement</kwd></kwd-group></article-meta></front></article>
