Introduction: Histoplasmosis is caused by Histoplasma capsulatum which is a dimorphic fungus. Most cases are mild or asymptomatic. Primary cutaneous histoplasmosis is rare entity. Case History: A-37 year old female patient residing in Nagpur (Maharashtra) presented with complaints of generalized weakness and skin colored papules and nodules over face, chest, back, both upper extremities and oral cavity since 1 month which was associated with night sweats, loss of appetite, arthralgia and myalgia. Cutaneous examination exposed multiple skin-colored nodules and papules ranging from 0.5 to 2 cm disseminated on face, chest, back, upper extremities and oral cavity. Discussion: Cutaneous histoplasmosis usually occurs secondary to pulmonary histoplasmosis. It presents as petechial/ecchymotic purpura, usually on anterior abdominal wall and thorax. Amongst the mucous membranes, oral cavity is most commonly involved. Disseminated variants are found most commonly in AIDS and organ transplant patients. Laboratory diagnosis is done by direct examination and culture on specimens in the form of sputum, bone marrow, lymph node aspiration and biopsy and peripheral blood film. Direct examination is done with wet KOH mount, PAS and Giemsa stain. Culture is done on Sabouraeds dextrose agar with incubation at 25 and 370 C. Mainstay of treatment is oral amphotericin B, alternative being oral itraconazole in all immunocompetent patients, except in meningitis patients. Conclusion: Histoplasmosis is common in immunocompromised patients and rarely in immunocompetent ones. Cutaneous histoplasmosis is even rarer in an immunocompetent patient, as compared to other presentations of the disease.