Macaranga Peltata belonging to Euphorbiaceae family is widely distributed in south east Asia. The plant parts leaves and stem bark were separated, shade dried and extracted separately using methanol. The concentrated methanolic extracts of Macaranga Peltata were subjected to phytochemical analysis and antioxidant evaluation by four different methods. The percentage yield of the leaves and stem bark were found to be 47% and 30% respectively. The antioxidant activity of the plant was carried out using four methods viz., DPPH free radical scavenging activity, Nitric Oxide radical inhibition Assay, Scavenging of Superoxide radical by Alkaline DMSO method and ABTS free radical scavenging activity. Stem Bark extract showed IC50 value of 10.13, 9.77 by DPPH and ABTS methods respectively. Leaf extract showed IC50 value of 14.85 for DPPH Assay and 7.61 for ABTS method. But both Stem Bark and Leaf extract showed very good activity for NBT Assay and nitric oxide radical inhibition activity and their IC50 values were very close to the Standard anti-oxidants ascorbic acid and Rutin.