Introduction: Stem cells are pluripotent cells that differentiate and proliferate in desired manner while nanoparticles are the particles of nanometer size used in various applications. Nanoparticles and stem cells interaction i.e. stem cell nanotechnology has opened the innovative area of research and applications in medical sciences. Objective: In this review, we aimed to research pharmacology of nanoparticles i.e. nanodrugs in stem cells. Method: We searched Google scholar, Pubmed, Medline, and other online as well as offline data base with key words of stem cells, nanoparticle, nanotechnology and nanopharmaceutics to retrieve the data. Articles were further sorted out regarding the availability of information. Only those articles, which were available by open access either full paper or abstract or both were included in the review. Result __ampersandsignamp; Conclusion: We conclude that stem cell nanotechnology is newest area of study in pharmacology. Different pharmacodynmic and pharmacokinetic aspect of nanoparticles as nanodrug should be explored before their inclusion on wide scale. These data warrant the establishment of Stem Cell Nanophrmaceutics as new branch of pharmacology to deal with nanodrugs and stem cells.