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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="healthcare" lang="en"><front><journal-meta><journal-id journal-id-type="publisher">IJCRR</journal-id><journal-id journal-id-type="nlm-ta">I Journ Cur Res Re</journal-id><journal-title-group><journal-title>International Journal of Current Research and Review</journal-title><abbrev-journal-title abbrev-type="pubmed">I Journ Cur Res Re</abbrev-journal-title></journal-title-group><issn pub-type="ppub">2231-2196</issn><issn pub-type="opub">0975-5241</issn><publisher><publisher-name>Open Science Publishers LLP</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">116</article-id><article-id pub-id-type="doi"/><article-id pub-id-type="doi-url"/><article-categories><subj-group subj-group-type="heading"><subject>Healthcare</subject></subj-group></article-categories><title-group><article-title>EVALUATION OF PROLONGED QT INTERVAL AMONG UNCOMPLICATED OBESE YOUNG MALES&#13;
</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ray</surname><given-names>Subhashree</given-names></name></contrib><contrib contrib-type="author"><name><surname>Devi</surname><given-names>Ellora</given-names></name></contrib><contrib contrib-type="author"><name><surname>Sahu</surname><given-names>Samir</given-names></name></contrib><contrib contrib-type="author"><name><surname>Rao</surname><given-names>E. Venkata</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><day>30</day><month>10</month><year>2013</year></pub-date><volume>04</volume><issue>02</issue><fpage>37</fpage><lpage>43</lpage><permissions><copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement><copyright-year>2009</copyright-year><license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p></license></permissions><abstract><p>Introduction: WHO reports overweight and obesity as the fifth leading risk factor for global deaths. Obesed subjects are more prone to ventricular arrthymias and sudden death. Aim of the study-We evaluated the interval b/w Q __ampersandsignamp; T waves (QT interval) in a 12 lead electrocardiogram among obese young males without comorbidities. Research Methods and Procedure: The study comprised of 111 young males grouped into 51 obese subjects and 60 healthy controls depending upon their BMI and WC in accordance with NIH guidelines. The QT interval was recorded by 12 __ampersandsignndash;lead ECG, measured manually __ampersandsignamp; corrected according to Bazett__ampersandsignrsquo;s formula. Exclusion criteria-The study group selected were healthy young males who had no diabetes, hypertension, cardiovascular disease, psychiatric problems __ampersandsignamp; h/o of alcohol abuse. Result: In the present study, the mean QTc values for control groups were within the normal range(QTc-422.9__ampersandsignplusmn;27.6 ms) and for cases QTc was (443.4__ampersandsignplusmn;20.48 ms) which was found to be significantly prolonged(p__ampersandsignlt;0.001). When age and sex matched controls, with mean BMI(22.86__ampersandsignplusmn;3.1kg/m2 ),and mean WC(88.1__ampersandsignplusmn;11.5 cm),were compared with obese males mean BMI(29.9__ampersandsignplusmn;3.1 kg/m2 ),and mean WC (105.2__ampersandsignplusmn;11.6 cm)which was found to be statistically significant(p__ampersandsignlt;0.01).Using Pearsons correlation analysis we found QTc statistically correlated with BMI (r=0.403 and p,0.01) and WC(r=0.326 __ampersandsignamp; p__ampersandsignlt;0.01). QTc did not correlate with age, Blood pressure and metabolic variables significantly. Conclusion: Prolonged QTc interval is associated with vulnerability to cardiac arrhythmias and sudden death in future among these uncomplicated obese young men. Hence, sustained weight loss is a safe method to ameliorate CVS complications.&#13;
</p></abstract><kwd-group><kwd>Uncomplicated obesity</kwd><kwd> QTc</kwd><kwd> BMI</kwd><kwd> Waist circumference.</kwd></kwd-group></article-meta></front></article>
