The authors investigated, in a randomized, placebo-controlled, single-blinded study, the efficacy and safety of lornoxicam in pain during dressing of burn patient with 2nd degree burns and on tramadol consumption in burn patients. Fifty patients were randomized to receive either lornoxicam (8mg) or tramadol (50 mg) and vice versa. The evaluation was performed with visual analogue (VAS) pain scores by encircling the pain score immediately after the dressings and 2 hrs after the same, and overall patient satisfaction. Both the drugs lornoxicam and tramadol were effective in reducing the pain score in burn patient. We conclude that lornoxicam is non-inferior to tramadol in reducing burn pain.