IJCRRI Journ Cur Res ReInternational Journal of Current Research and ReviewI Journ Cur Res Re2231-21960975-5241Open Science Publishers LLP110HealthcareHYPOTHYROID GOITRE ASSOCIATED WITH EXCESS IODINE AMONG SOUTH INDIANS __ampersandsignnbsp; __ampersandsignnbsp; PichandiSureshVSathyaPJanakiramanKRamadevi3001201404052938This article is copyright of Popeye Publishing, 20092009This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.

Aim and Objectives: The aim of this study is to assess the iodine nutritional status in hypothyroid patients with goitre attending a major teaching hospital in south India by measuring urinary iodine excretion and to correlate with the thyroid hormone status. Methods: One hundred and fifty patients with Overt Hypothyroid goitre and one hundred euthyroid healthy, non-goitrous volunteers were included. Results: Free thyroxine (FT4), TSH and urinary iodine concentrations (UIC) were measured for all the patients and controls. The hypothyroid patients had higher iodine levels than control subjects (236.59 __ampersandsignplusmn; 133.59Vs150.46 __ampersandsignplusmn; 19.48, p__ampersandsignlt;0.05). Among patients there was a significant positive correlation between UIC and TSH levels. Also, a significant positive correlation between UIC and FT4 was found. Conclusion: We conclude that excessive iodine intake may trigger thyroid dysfunction and eventually lead to hypo function of the thyroid gland.

hypothyroidism Urinary iodine goitre iodine deficiency disorders.