Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241EnglishN2022October18HealthcareFormulation Development and Characterization of Ointments containing Bambusa arundinacea Extract and Chlorophytum borivilianum Extract English0105Ritu NandalEnglishRitu Nandal, Assistant Professor, R. S. M. College of Pharmacy, Lakhu, Buana, Panipat 132145, Haryana, India. https://doi.org/10.31782/IJMPS.2022.121001The goal of the current study was to investigate potential applications for extracts of Bambusa arundinacea (resin) and Chlorophytum borivilianum (rhizome) used in ointment formulations. The pharmaceutical properties of the formulations, such as pH, the skin irritancy test, viscosity, appearance, extrudability, spreadability, washability, and swelling index, were evaluated. The skin irritation test inquiry found that no particular edema or erythema symptoms appeared after therapy for continuous seven days. pH measurements of the formulations were 6.3 (F1) and 6.7 (F2). While F2 showed edema of 1.29%, F1 showed swelling of 1.42%. The two ointment compositions’ respective spreadabilities were 6.5 g.cm/sec and 6.0 g.cm/sec. The formulae for F1 and F2 were found to be +++ and +++, respectively, extrudable from the collapsible tubes. In light of the formulations’ rheological characteristics, the viscosity was found to be 5300 cps (F1) and 6200 cps (F2). The washability of the formulations was found to be +++ for Formulation-1 and +++ for Formulation-2. By making this finding, which also revived the ideas of ethnopharmacology in connection to modern medicine, the uses of polyherbal formulations in conventional medicine were made clear. English Extract, Ointment, Formulation, Characterization, Bambusa arundinacea, Chlorophytum borivilianumhttp://ijcrr.com/abstract.php?article_id=214http://ijcrr.com/article_html.php?did=2141. De Smet PA. Herbal remedies. New Eng J Med. 2002;347(25):2046-56. 2. Jivani NP. Phytopharmacological properties of Bambusa arundinacea as a potential medicinal tree: An overview. J Appl Pharm Sci. 2011;1(10):27-31. 3. Khanam Z, Singh O, Singh R, Bhat IU. Safed musli (Chlorophytum borivilianum): A review of its botany, ethnopharmacology and phytochemistry. J Ethnopharmacol. 2013;150(2):421-41. 4. Cooper JW, Gunn C. Cooper and Gunn’s Tutorial Pharmacy. CBS Publishers & Distributors; 1986. 5. Shivhare RS, Awchat P, Mahapatra DK, Ingole AR, Borkar SS. Development of Wound Healing Ointment Formulation containing Active Extracts of Tridax procumbens, Calendula officinalis, Murraya koenigii, and Aloe barbadensis. Int J Pharm Phytopharmacol Res. 2019; 9(6): 99-104. 6. Shivhare RS, Kamble MA, Mahapatra DK, Ingole AR, Baheti JR. Development of mosquito repellant gel formulations from various natural volatile oils: a comparative study with the marketed formulation odomos®. J Drug Deliv Ther. 2018;8(6):106-10.

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-5241EnglishN2022October18HealthcarePharmacognostic Evaluation of Trachyspermum Ammi (Ajwain Seeds) Seed Extract for Vulvovaginal Candidiasis (VVC)         English0613Md. Rageeb Md. UsmanEnglish G. P. VadnereEnglish Snehal PawarEnglishDr. Md. Rageeb Md. Usman, Department of Pharmacognosy, Smt. Sharadchandrika Suresh Patil College of Pharmacy, Chopda, Maharashtra, India https://doi.org/10.31782/IJMPS.2022.121002EnglishApiaceae, Antimicrobial, Trachyspermum ammi, Antifungal, Vulvovaginal candidiasis, Seedshttp://ijcrr.com/abstract.php?article_id=215http://ijcrr.com/article_html.php?did=2151. Wani AR, Yadav K, Khursheed A, Rather MA. An updated and comprehensive review of the antiviral potential of essential oils and their chemical constituents with special focus on their mechanism of action against various influenza and coronaviruses. Microb. Pathog.2021Mar; 152: 104620.https:// doi.org/10.1016/j.micpath.2020.104620 2. Gonçalves B, Ferreira C, Alves CT, Azeredo J, SilvaS. Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors. Crit. Rev. Microbiol. 2016 Nov;42(6):905-27.https:// doi.org/10.3109/1040841X.2015.1091805 3. Lizarraga-Valderrama LR (2021). Effects of essential oils on central nervous system: Focus on mental health. Phytother Res. 2021 Feb;35(2):657-679.https://doi.org/10.1002/ptr.6854 4. Marrazzo J (2002). Vulvovaginal candidiasis. BMJ. 2002 Sep 14;325(7364):586. 5. Anil Kumar KR, Saritha V, Fahath K, Bawa SA (2009). Ameliorative effect of Ajowan extracts on hexachlorocyclohexane-induced lipid peroxidation in rat liver. Food Chem. Toxicol. 2009 Feb;47(2):279-82 6. Asima C, Chandraprakashi S. The Treatise of Indian Medicinal Plants., Publication and Information Directorate CSIR: New Delhi; 1995; 4: 45-47. 7. She M, Pu F, Pan Z, Mark FW, John FMC, Ingrid H-S etal. (2005). Apiaceae (Umbelliferae). Flora Chin 14; 1-205. 8. Balaji G, Chalamaiah M, Ramesh B, Reddy Y (2012). Antidiarrheal activity of ethanol and aqueous extracts of Carum copticum seeds in experimental rats. Asian Pac J Trop Biomed 2, S1151-S1155. 9. RamaswamyS, Sengottovelu S, Sherief SH, Jaikumar S, Saravanan R, Prasad Kumar C et al. (2010). Gastroprotective activity of ethanolic extract of Trachyspermum Ammi fruit. Int J Pharm Bio Sci 1, 1-15. 10. 6. Arrigoni Martellie E. Inflammatory and Anti-inflammatory. Spectrum Publication, Inc., New York, 1977, pp. 119-120  11. Aftab K, Atta-Ur-Rahman, Usmanghani, K, 1995. Blood pressure lowering action of active principle from Trachyspermum ammi (L.) Sprague. Phytomedicine.1995 Jul;2(1):35-40.  12. Boskabady M, Shaikhi J (2000) Inhibitory effect of Carum compticum on histamine (H1) receptors of isolated guinea-pig tracheal chains. J Ethnopharmacol 69; 217-227.  13. Srivastava KC (1988) Extract of spice-rum (Trachyspermum ammi)-shows antiaggregatory effects and alters arachidonic acid metabolism in human platelets. Prostaglandins Leukot Essent Fatty Acids. Jul; 33(1):1-6.  14. SrivastavaM, Baby P, Saxena A (1999). GC-MS investigation and antimicrobial activity of the essential oil of Carum copticum benth and hook. Acta Aliment. 28 (3); 291-295.