Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410403EnglishN2013November30HealthcareASSESSMENT OF REGULATORY PEPTIDES AND HORMONES IN SIMPLE OBESE SUBJECTS     English0108Kalpana SinghEnglish Bhawna SinghEnglish Jitendra RaoEnglish Anu ChandraEnglish Aparna MisraEnglish Ajanta RoyEnglishObjectives: The aim of this study was to evaluate the secretory status of leptin, ghrelin, neuropeptide Y and galanin in simple obese subjects compared to normal weight subjects Material and Method: The study group consists of twenty subjects each of overweight (OW), obese (OB) and morbid obesity (MO) classified on the basis of body mass index (BMI) issued by Ministry of Health and Family Welfare, GOI for simple obesity. Thirteen subjects with BMI below 23kg/mt2 constituted the control group without any sign and symptom of diseases. Leptin, ghrelin, neuropeptide Y and galanin concentration were estimated by commercially available ELISA kit. Result: Serum leptin levels were significantly elevated in OW, OB and MO groups as compared to healthy non obese subjects. Mean neuropeptide Y and galanin levels were higher in OB and MO subjects as compared OW and normal weight subjects. While mean ghrelin levels were higher in normal weight and OB subjects as compared to OW and MO group. Except ghrelin, it was observed that with increasing BMI there was an increase in levels of leptin, neuropeptide Y and galanin which was also statistically significant (p value 0.7; p value Englishbody mass index, galanin, ghrelin, leptin, neuropeptide Y, obesityhttp://ijcrr.com/abstract.php?article_id=73http://ijcrr.com/article_html.php?did=73

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410403EnglishN2013November30HealthcareDOPPLER AND COMPUTED TOMOGRAPHY EVALUATION OF CAROTID CAVERNOUS FISTULA : A CASE REPORT English0913Mitesh KatariyaEnglish Sandeep ShindeEnglish Prasanna DeochakeEnglish Dilip LakhkarEnglishWe present here a case of carotid cavernous fistula (CCF) which is an abnormal communication between carotid artery system and cavernous system which was diagnosed with help of non invasive and easily available techniques as dopplerand contrast enhanced Computed tomography (CT) scan. EnglishCarotid cavernous fistula, Trauma, Doppler, CT scanhttp://ijcrr.com/abstract.php?article_id=85http://ijcrr.com/article_html.php?did=85

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410403EnglishN2013November30HealthcareSYNERGISTIC NOOTROPIC EFFECT OF LOW DOSE ASPIRIN AND ONDANSETRON: AN ANIMAL STUDY English1419Nema PallaviEnglish Totade SangitaEnglish Gupta C.DEnglishObjective: To evaluate synergistic nootropic effect of low dose aspirin and Ondansetron in rats. Material and Methods: Retention of conditioned avoidance response was assessed using repeated electroconvulsive shock in rats. Electroconvulsive shock was used to induce amnesia. Rats were divided into five groups: control (pretreated with distilled water), Electroconvulsive shock (150 V, 50 Hz sinusoidal with intensity of 210 mA for 0.5 s), combined Electroconvulsive shock and aspirin (7.5mg/kg) pretreated groups, combined Electroconvulsive shock and ondansetron (0.4 mg/kg) pretreated groups, combined Electroconvulsive shock, aspirin (7.5mg/kg) and ondansetron (0.2 mg/kg) pretreated groups. Data was analyzed by ANOVA followed by Dunnet’s test. Result: Findings showed that administration of single Electroconvulsive shock daily for consecutive 8 days results in disruption of the retention of conditioned avoidance response. Ondansetron and aspirin significantly prevented Electroconvulsive shock -induced attenuation of the retention of conditioned avoidance response. Combined Aspirin and subnootropic dose of Ondansetron prevented Electroconvulsive shock - induced attenuation of the retention of conditioned avoidance response which is significantly higher than aspirin alone. Conclusion: This study concludes, Aspirin might inhibit this serotonergic transmission and results in its neuroprotective action. When aspirin is combined with 0.2 mg/kg of ondansetron, retention of CAR was significantly higher than aspirin alone. EnglishConditioned avoidance response, Aspirin, Ondansetron, Electroconvulsive shock, serotonergic transmission.http://ijcrr.com/abstract.php?article_id=94http://ijcrr.com/article_html.php?did=94

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410403EnglishN2013November30HealthcareA STUDY ON BEHAVIORAL RISK FACTORS OF CARDIO VASCULAR DISEASES (CVDS) AMONG PATIENTS ATTENDERS OF PATIENTS ADMITTED IN IN-PATIENT DEPARTMENTS OF MC GANN HOSPITAL, SHIMOGA, KARNATAKA, SOUTH INDIA English2028Raghavendraswamy KoppadEnglish Ravindra B. PatilEnglish Santosh Kumar A.English Madhusudan M. V.English Prashanth H. L.English Chandrashekhar S. V.EnglishEnglishCardio Vascular diseases (CVDs), Non Communicable Diseases (NCDs), Behavioral Risk factorshttp://ijcrr.com/abstract.php?article_id=102http://ijcrr.com/article_html.php?did=102

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410403EnglishN2013November30HealthcareGRADES OF EVIDENCES IN DRUG INFORMATION PROVIDED AT A RURAL INDIAN HOSPITAL English2933Seeba ZachariahEnglish C. SowmyaEnglish Dixon ThomasEnglishBackground: There are two aspect of quality in drug information service, one is the quality of information available, and another is the quality method of getting, processing, and delivering it. In this article we study about the quality of drug information available for the queries requested by different health care professionals. Methods: The study was performed on a drug information service in a rural Indian hospital in 2011 and 2012. The U.S. Preventive Services Task Force (USPSTF) grading system was used for grading the quality of evidences for clinical uses of drugs. Results: Total number of queries answered in 2011 and 2012 was 726. Majority of the queries were from nurses 448, followed by doctors 140, and pharmacists 77. Other queries came from nutritionist (35), student nurses (19), and laboratory technicians (07). Ninety six percentage of information requested by nurses were available with good quality evidences. Evidences on available information requested by doctors were mostly 46% fair or poor 34% and of pharmacists was 51 % fair. Conclusion: Nurses do request information in the late stages of clinical decision making and the doctors or pharmacists were requesting information in the early stages of clinical decision making to a drug information service. Doctors mostly asked difficult queries to answer than other professionals. Englishdrug information, evidences, clinical, gradehttp://ijcrr.com/abstract.php?article_id=109http://ijcrr.com/article_html.php?did=109