Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410311EnglishN2013July26HealthcareCRANIAL INDEX - SEX DETERMINATION PARAMETER OF ADULT HUMAN SKULLS IN SOUTH INDIAN POPULATION English0106Shanthi Ch.English V. Subhadra DeviEnglish S. LokanadhamEnglish B. Ravindra KumarEnglishThere were many parameters to bring out the sex, ethnicity and race based on morphometry of skull. Cephalic index is one of the important parameter in sex determination and classification of human crania. In the present study, an attempt was made to report the sexual dimorphism in 100 human crania of known sex based on the cranial index. Maximum Cranial Breadth (MCB) and Maximum Cranial Length (MCL) were measured and the cranial index was calculated as per the formula. Descriptive statistics was applied to find the significance of the parameters in determining the sex. The mean maximum cranial breadth in female was 11.8±0.81 and in male was 12.2±0.68.The mean maximum cranial length in female was 16.4±0.69 and in male was 17.5±0.74.Considering the above parameters individually both of them were observed to be significant with pEnglishhttp://ijcrr.com/abstract.php?article_id=55http://ijcrr.com/article_html.php?did=55

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410311EnglishN2013July26HealthcareRUPTURED INTRACRANIAL DERMOID- A CASE REPORT English0710Athawale KedarEnglish Lakhkar DilipEnglish Bhagat SangramEnglishIntracranial dermoids rarely rupture. They are associated with significant risk of morbidity and mortality when they rupture. The rupture within the ventricle is further rarer. Case report: We present a case of intraventricular rupture of a dermoid cystic tumor along with dissemination of subarachnoid fat. The diagnosis was made on CT scan and MRI imaging. The patient died in few days from chemical meningitis. Intracranial dermoid cystic tumors account for English Intracranial dermoid, Intraventricular rupture, Chemical meningitis.http://ijcrr.com/abstract.php?article_id=57http://ijcrr.com/article_html.php?did=57

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410311EnglishN2013July26HealthcareSTUDY OF DEATHS DUE TO THERMAL BURNS IN AND AROUND GULBARGA CITY English1116Saranabasavappa KaraddiEnglish Anand MugadlimathEnglish Prakash BabladiEnglish D.B KulkarniEnglish Rekha HiremathEnglishThe present study included all cases of death due to thermal burns brought to the mortuary of Government General Hospital, attached to Gulbarga between July 2003 to June 2008. During the study period a total of 698 cases of deaths due to thermal burns were studied. The incidence of death due to burns is 25.41%, maximum number of death 44.84% occurred in the age group 21-30 years. Female outnumbered males by about 3-times i.e., in a ratio of 3:1 and out of 511 females 74.39% were married and 25.61% were unmarried. 17.34% of victims could not survive for more than 12 hours whereas 30.66% of victims died after 5 days of incident and 21.63% of victims died with 80- 90% burns most of the victim (65.54%) died due to septicemic shock. It was also observed 85.67% of the victims had accidental burns. Out of total dowry death cases 60.08% were due to burns. EnglishThermal burns; Septicemia; Dermo-epidermal burnshttp://ijcrr.com/abstract.php?article_id=58http://ijcrr.com/article_html.php?did=58

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410311EnglishN2013July26HealthcareTOPOCHEMICAL STUDIES ON 4(3H)-QUINAZOLINONES AS DIHYDROFOLATE REDUCTASE (DHFR) INHIBITORS: AN APPROACH TO PREDICT THE ANTITUMOR ACTIVITY English1727Ramesh M.English Balakumar C.EnglishBackground of study: Inhibition of DHFR is one of the potential targets for anticancer therapy. In this study, topochemical descriptor based calculations were carried out on substituted 4(3H)-quinazolinones to predict DHFR inhibition. A data set of 50 molecules of substituted 4(3H)-quinazolinones as potential DHFR inhibitors and its topological descriptors like Wiener’s index, Balaban’s index and Molecular topological index were investigated. Objective: The topological data was systematically analyzed and suitable descriptor based topochemical models were developed after the identification of the active ranges. Research methodology: Subsequently, the DHFR inhibition activity was predicted for all the data set of molecules using topochemical models. Then, the predicted activity was compared with the experimentally reported DHFR inhibitor activity. Results: The overall prediction of DHFR inhibition was found to be higher accuracy of 80% for the models based on Wiener’s index as well as Molecular topological index and 74% for Balaban’s index. Conclusions: The prediction of DHFR inhibition using topochemical descriptors can be useful to design newer analogues of quinazolines as potential DHFR inhibitors. EnglishDihydrofolate reductase, Wiener’s index, Balaban’s index, Molecular topological index and 4(3H)-quinazolinone, Antitumor action.http://ijcrr.com/abstract.php?article_id=60http://ijcrr.com/article_html.php?did=60

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410311EnglishN2013July26HealthcareSTUDY OF VARIATIONS IN THE MEDIAL LONGITUDINAL ARCH LEADING TO DEVELOPMENT OF ADULT ACQUIRED FLAT FOOT English2837Subhra MandalEnglish Prabir MandalEnglish Ranjan BasuEnglishIntroduction: Knowledge of the biomechanics of the arch of adult foot is really important to assess the variations in the Medial Longitudinal Arch(MLA) and categorizing the aetiology of Adult Acquired Flatfoot (AAF). Both the static and dynamic footprint parameters were studied. Materials and Methods: Bengali adult patients of age group 20 to 30 yrs. (of both sexes) at I.P.G.M.E. & R , Kolkata and NIOH , Kolkata ,with or without foot pain symptoms were included in the study . Static footprint parameters like footprint ratio or Staheli's Arch Index (AI) and the ratio of Vertical Height of Navicular (Arch Height) and lowest palpable medial part of talus from ground level (Medial Arch Height) was measured. Lateral radiographs of the foot with ankle and knee immobilized were taken to estimate AH & MAH. The other attributing factors like increased Body Mass Index , obesity (mainly in females), Posterior Tibialis Tendon dysfunction and incidence of plantar fasciitis were also measured. Data Obtained were analyzed and presented with counts and percentage. Results : Dynamic footprint parameters – like Contact Force Ratio and Navicular Drop were estimated at the Gait Lab of N.I.O.H. through a capacitance platform . A significant correlation between the two variables was elicited through a scatter diagram accounting for the aetiology of AAF. Incidence of accessory navicular or subluxation of talocalcaneonavicular joint (TCN) or laxity of spring ligament having an effect on MLA could not be traced in the present study though shown by previous authors. Conclusion: The resultant conclusion creates immense potential in the field of conservative management - like specially designed footwear for AAF or surgical correction of AAF in athletes or military personnel. EnglishMedial longitudinal arch(MLA), Arch index(AI), AAF, AH, MAH, Capacitance platform, Contact force ratio, Navicular drop, PTT dysfunction, Plantar fascitis, Obesity, Subluxation of TCN joint, Accessory navicularhttp://ijcrr.com/abstract.php?article_id=62http://ijcrr.com/article_html.php?did=62

Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410311EnglishN2013July26HealthcareTHE CADAVERIC STUDY OF EXTENSOR CARPI RADIALIS LONGUS MUSCLE ON THE DEVELOPMENTAL BASIS English3842Sharadkumar Pralhad SawantEnglishAim: To study the extensor carpi radialis longus muscle in 100 cadavers. Materials and Methods: This study on extensor carpi radialis longus was performed on 100 (200 specimens of superior extremities) embalmed donated cadavers (90 males & 10 females) in the department of Anatomy of K.J.Somaiya Medical College, Sion, Mumbai, India. Observations: Out of 200 specimens the variation was observed in 22 specimens. The extensor carpi radialis brevis was absent and the extensor carpi radialis longus was giving two tendons in the second compartment of extensor retinaculum before its insertion while passing deep to the abductor pollicis longus. The one tendon of extensor carpi radialis longus inserted into the radial side of the dorsal surface of the base of the second metacarpal bone while the other tendon inserted into the lateral dorsal surface of the base of the third metacarpal bone, with a few fibres inserting into the medial dorsal surface of the second metacarpal bone. The variant extensor carpi radialis longus was supplied by the radial nerve. The finding was noted after thorough and meticulous dissection of the upper limbs of both sides. The arterial pattern of upper limb were also observed. The variation was unilateral. The left upper limb was normal. The photographs of the variations were taken for proper documentation. Conclusions: The variant extensor carpi radialis longus muscle is clinically important for surgeons dealing with entrapment or compressive neuropathies, orthopaedicians operating on the fractures of the lower end of the humerus, anaesthetist performing pain management therapies on the upper limb and physiotherapist doing electromyography for evaluating and recording the electrical activity produced by skeletal muscles. A lack of knowledge of such type of variations might complicate surgical repair. EnglishExtensor Carpi Radialis Longus, Variation, Radial Nerve, Surgeons, Compressive Neuropathies, Orthopaedicians, Fractures, Anaesthetist, Pain Management Therapy, Physiotherapist, Electromyography.http://ijcrr.com/abstract.php?article_id=65http://ijcrr.com/article_html.php?did=65