Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410310EnglishN2013June25HealthcareASSESSMENT OF KNOWLEDGE, ATTITUDE AND PRACTICE AMONG WOMEN OF CHILD BEARING AGE TOWARDS CONTRACEPTIVE DRUG UTILIZATION IN ADAMA (KEBELE 12)
English0108Esubalew KumssaEnglish Wubayehu KahaliwEnglish Zeryawekal ErgetieEnglishBackground: Population growth is a major concern in developing countries in view of its impact on broader socio-economic development. In Ethiopia, contraceptive prevalence rate is 4.1-39 Objective: To assess knowledge, attitude and practice among women of childbearing age towards contraceptive drug utilization in Adama (kebele 12) Materials and methods: A community based descriptive cross-sectional study was carried out on a target population of all women age 15 to 49 years and reside for six months in Adama town (Kebele 12). Data collection was acomplished by interviewing using structured questionnaires. 361 women were interviewed during the data collection period who had been living in Adama town for more than 6 months. The data obtained was analyzed using Microsoft office excel 2007. Results: Educational level of 329(90.9%) of the interviewed population attendees varies from Can read and write to higher education, while 32(8.8%) of them were illiterate. Married women accounts 289(80.1%) and the unmarried accounts 72(19.9%). Out of 361 interviewed women in childbearing ages, 347(96.2%) of them knew about family planning method. The majority of the women in childbearing ages interviewed showed that 330(94.2%) of them were experienced to use contraception methods. Conclusion: According to the result of this study, the majority of the respondents had good knowledge attitude and practice towards contraception drug utilization. Some of the respondents thought the major factor affecting the utilization of family planning service was inadequate information and education towards family planning service. Long distance of health facility from their home and poor relationship between service provider and consumer are also additional factors affecting contraceptive drug utilization program.
EnglishContraception, Women in child bearing age, family planning, combined pillhttp://ijcrr.com/abstract.php?article_id=15http://ijcrr.com/article_html.php?did=15Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410310EnglishN2013June25HealthcareCHARACTERIZATION AND EVALUATION OF BILAYERED TABLETS OF METFORMIN AND GLIMEPIRIDE
English0916Khushbu ShenghaniEnglish Yogesh ChaudhariEnglish Suresh KumavatEnglish Priyanka BoroleEnglish Pankit ShahEnglishBi-layer tablets containing two layers, one the immediate release and one containing the extended release layer. Extended layer were prepared by wet granulation method using different viscosity grade of Hydroxypropyl methylcellulose (HPMC K100M and HPMC K200M) as polymers and immediate release layer were prepared by wet granulation method using superdisintegrant such as sodium starch glycolate and crosscarmellose sodium. Binder used was polyvinyl pyrollidone (PVP K-30). The tablets were then evaluated for the various physicochemical parameters and for the dissolution profile and then the prepared batches were compared with the Reference product. All the values were found to be within limit. The formulations (G5M8) having immediate release layer produces immediate effect within 45 second followed by extended release (95.47%) at 10 hrs and it comparable with innovator. The present study concluded that Bilayer tablets of Metformin Hydrochloride as an extended release layer and Glimepiride as an alternative to the immediate release conventional dosage form.
EnglishBilayer; Glimepiride; Metformin; HPMC K100M; HPMC K200M; Extended Release.http://ijcrr.com/abstract.php?article_id=21http://ijcrr.com/article_html.php?did=21Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410310EnglishN2013June25HealthcareIMPACT OF ACNE ON QUALITY OF LIFE- A GENDER BASED STUDY
English1722Haritha SamanthulaEnglish Madhavi KodaliEnglish Anusha GuttaEnglishBackground of study: Although acne is generally self-limited, it is found to have a great impact on patients’ lives. Objective: The purpose of the present study was to assess the impact of acne on Quality of Life in relation to gender, duration and severity of acne. Research Methodology: 100 male and 100 female patients with Acne vulgaris affecting the face between the age group 11-25 years were included in our study. After obtaining the history, the acne was graded into mild, moderate and severe based on the type and number of lesions. Dermatology Life Quality Index (DLQI) and Cardiff Acne Disability Index (CADI) were administered on the patients to measure the Quality of Life. Results: Based on the DLQI scores 81% had an effect on Quality of Life (QOL). The impact of acne was extremely large in 25% and very large in 56% of the study population. As per the CADI score 130 patients (65%) had a large impact on quality of life. The QOL in females was affected more than males based on CADI (pEnglishAcne vulgaris, CADI, Quality of Life.http://ijcrr.com/abstract.php?article_id=34http://ijcrr.com/article_html.php?did=34Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410310EnglishN2013June25HealthcareASSESSMENT OF KNOWLEDGE, ATTITUDE, PRACTICE, RISK FACTORS AND ASSOCIATED CO-MORBIDITIES IN DIABETES PATIENTS
English2330Amit GujratiEnglish Bhuwan SharmaEnglish Mohini JogdandEnglishBackground of study: It is estimated that 20 percent of the current global diabetic population resides in South East Asia region. Type 2 diabetes is the commonest form of diabetes globally as well as in India. It constitutes more than 95% of the diabetic population in our country. The number of people with diabetes in India, currently around 40.9 million is expected to rise to 69.9 million by 2025, unless urgent preventive steps are taken. Aim: To assess KAP, risk factors and associated co-morbidities in diabetic patients residing in an urban slum of Mumbai, India Research Methodology: The present community based descriptive epidemiological study was conducted during the period of October 2010 to September 2012. A total of 272 known diabetic patients were selected from the community by employing simple random sampling. Socio demographic profile, knowledge, attitude and practices related to diabetes were collected using of semi-structured, pre-tested questionnaire after taking informed verbal consent. Examinations such as height, weight, body mass index (BMI), blood pressure and blood sugar were done with appropriate techniques. Data was analyzed using SPSS ver. 19 and appropriate tests were applied. Results: Out of 272 patients, 88.2%, 88.7%, 83.8% patients had poor knowledge, attitude and practices scores respectively. A significant association was found between the blood sugar level and body mass index (pEnglishCo-morbidities, Diabetes, KAP, Risk factors, Urban slumhttp://ijcrr.com/abstract.php?article_id=42http://ijcrr.com/article_html.php?did=42Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410310EnglishN2013June25HealthcareRED CELL ALLOIMMUNIZATION IN MULTI TRANSFUSED PATIENTS WITH BETA THALASSEMIA MAJOR - A STUDY FROM SOUTH INDIA
English3140Bhaskar ShenoyEnglish Murali Mohan VoonaEnglish Shivaram CEnglish NijagunaEnglish ShivanandaEnglishBackground of study: Beta thalassemia is one of the commonly inherited genetic disorders and public health problem in India. Though hemotransfusion is the primary option to manage beta thalassemia, it may be associated with occurrence of red cell alloimmunization. Aim / Objective: The purpose of this study is to determine the prevalence, types and factors determining the alloantibodies in thalassemic children. Research Methodology: This cross sectional study comprised of 74 children of south India receiving regular blood transfusions. Study subjects were screened for the presence and type of alloantibodies. The details regarding previous transfusions were also collected using a predesigned profoma. Results: The prevalence of alloantibodies was 9.46% in the study group. Alloantibodies were common in thalassemic children of more than 14 years, females, non-splenectomised children, who initiated the transfusion at the age of less than six months, with B and O blood group and those who had undergone more than 150 transfusions. Anti – C and Anti-kell antibodies were the most prevalent antibodies in the study group. Conclusion: Since these alloantibodies are haemolytic, appropriate treatment and care is necessary especially in thalassemic children and new strategies should be implemented to cut short the occurrence of erythrocyte alloimmunization.
EnglishBeta-thalassemia, blood transfusion, alloantibodies.http://ijcrr.com/abstract.php?article_id=47http://ijcrr.com/article_html.php?did=47Radiance Research AcademyInternational Journal of Current Research and Review2231-21960975-52410310EnglishN2013June25HealthcareQUALITY OF LIFE AND COPING STYLES OF CAREGIVERS OF PATIENTS SUFFERING FROM THALASSEMIA MAJOR
English4148Saira MajidEnglish Muazzama AbidiEnglishThe most common genetic disease in Pakistan is Thalassemia. The objective of this research was to find the relationship between Quality of Life and Coping Styles in Caregivers of Patients suffering from Thalassemia Major. The sample for the present study consisted of 202 (Men=102; Women=100) caregivers of patients suffering from thalassemia major. Data was collected from caregivers of patients suffering from thalassemia major from two different institutes i.e, Thalassemia center, Rawalpindi and Fatimid foundation, Lahore. Urdu versions of World Health Organization Quality of Life Scale-Brief and Brief Cope were used. Alpha coefficient reliabilities, Pearson Product Moment correlation and Independent sample t test were run to fulfill the objective of the study. Results revealed a significant positive relationship between problem focused coping, positive coping and psychological state among caregivers of patients suffering from thalassemia major. Moreover, caregivers of patients suffering from thalassemia major undergoing chelation therapy scored high on relationship to salient features of environment as compared to caregivers of patients suffering from thalassemia major undergoing blood transfusions. On the contrary, caregivers of patients suffering from thalassemia major undergoing blood transfusions exhibited frequent use of coping styles as compared to caregivers of patients suffering from thalassemia major undergoing chelation therapy.
EnglishQuality of Life, Coping Styles, Caregivers, Thalassemia Major.http://ijcrr.com/abstract.php?article_id=52http://ijcrr.com/article_html.php?did=52